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The principal cytochrome P450 isoenzyme included appears for being CYP2E1, with CYP1A2 and CYP3A4 as added pathways. Close to 85% of an oral dose appears inside the urine in just 24 hours of administration, most as the glucuronide conjugate, with smaller amounts of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity data.On account of